PRP IN MAXILLOFACIAL SURGERY

The growth factors in platelets has been believed to have the potential to accelerate the healing process, promotes tissue repair and regeneration. The platelet rich growth factor promotes both hard (bone) and soft (skin and gingival) tissue healing. The PRP has a broad spectrum of applications in oral and maxillofacial surgery.

The success of maxillofacial reconstruction, dental implants, estheticdental procedures depends on hard and soft tissue regeneration. PRGF an intrinsic growth factor released by activated platelets is a regenerative therapy that promotes tissue healing. Factors like ease of application, cost effectiveness, reduced degree ofdonor site morbidity1and decreased risk of disease transmission has made the clinicians opt for PRGF like PRF and PRP.

PRP is an autologous modification of fibrin gel introduced by Gibbe and Ness in the year 1990. PRP hastens and boosts up the body’s wound healing mechanism by release of bio active substances like Platelet derived growth factor (PDGF), Transforming growth factor (TGF), insulin-like growth factor (IGF), and epidermal growth factor (EGF)2upon activation of platelets (by addition of thrombin)that constitute approximately 5% of the normal blood clot.